Electric guitar · solidbody
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| Body Style | solidbody |
| Top | Maple |
| Body | Mahogany (Ultra-Modern weight relief) |
| Neck | Mahogany |
| Fingerboard | Ebony |
| Neck Pickup | Burstbucker Pro Rhythm |
| Middle Pickup | Burstbucker Pro Mid |
| Bridge Pickup | Burstbucker Pro Plus Lead |
| Pickup Switch | 3-way Toggle |
| Controls | 3 Push/Pull Volume (Coil Tap), Master Tone |
| Construction | Glued In, with Modern Contoured Heel |
| Bridge | Aluminum Nashville Tune-O-Matic |
| Nut Width | 43.05 mm |
Artists documented playing the Gibson Les Paul Supreme: Ace Frehley, Billy Gibbons, Duane Allman, Gary Moore, Jimmy Page, Joe Bonamassa, Joe Perry, Peter Green, Randy Rhoads, Slash, Zakk Wylde.